Aquagenic syringeal acrokeratoderma with palmar sparing and apocrine metaplasia

Aquagenic Syringeal Acrokeratoderma

Aquagenic syringeal acrokeratoderma is a newly described disease entity of unclear etiology, affecting predominantly adolescents and young adults. It manifested as multiple whitish papules on the palms or rarely soles, which became accentuated after immersion in water and improved after drying the involved area. Burning, pain, pruritus or tightening sensation may be present and usually there is...

[Aquagenic syringeal acrokeratoderma].

improved to baseline status within 30 to 45 minutes. Based on clinical symptoms resembling aquagenic syringeal acrokeratoderma, we performed a histological study that revealed mild hyperkeratosis and discrete dilatation of the acrosyringium, of unclear pathological significance (Figure 2). Because the symptoms were similar to the alterations described at the palmarplantar level in patients with...

Permanent treatment of aquagenic syringeal acrokeratoderma with endoscopic thoracic sympathectomy.

1. van Osch LD, Oranje AP, Keukens FM, Voorst Vader van PC, Veldman E. Keratosis follicularis spinulosa decalvans: A family study of seven male cases and six female carriers. J Med Genet 1992;29:36-40. 2. Fong K, Wedgeworth EK, Lai-Cheong JE, Tosi I, Mellerio JE, Powell AM, et al. MBTPS2 mutation in a British pedigree with keratosis follicularis spinulosa decalvans. Clin Exp Dermatol 2012;37:63...

Translucent whitish papules on the palms after exposure to the water – aquagenic syringeal acrokeratoderma

Apocrine hidrocystoma with mucinous metaplasia.

Hidrocystoma is a rare cystic lesion arising from the sweat glands, and is classified into apocrine and eccrine variants, with the majority being of apocrine nature [1]. It is usually found in the head and neck region, and commonly affects the periorbital area [1, 2]. Apocrine hidrocystoma is characterized histopathologically by the presence of a unilocular or multilocular cyst situated in the ...